Abstract
We have developed infrastructure of the technologies and resources for post-human genome research to perform functional proteomics (the analysis of protein functions, protein-protein interactions, and human protein structures) on a large scale. A method for profiling autoantibodies in serum is developed using human protein expression resources and protein expression techniques. The human biological defense system responds to abnormalities in the body with extraordinary sensitivity. Hence, this system is an effective tool for detecting human diseases at an early stage. Health safety and security can be achieved by establishing an early diagnostic method for diseases using autoantibody profiling of blood with a protein array.