Exposure apparatus for the experimental studies on human health effects of air pollutants

Abstract

The data for establishment of standards for allowable levels for short term exposure to air pollutants can be obtained through epidemiological studies and experimental exposure studies.
Human experimental exposure studies of the health effects of air pollutants can be accomplished at fixed concentration under well controlled conditions, focusing attention on physiological testing and evaluation of symptoms. Specifically, this report will involve tests to assess the reaction of respiratory airway to O₃, SO₂ and NO₂ alone or in combination at 0.15, 0.3 or 0.5ppm with rest or intermittent exercise for two hours. Effects of these air pollutants exposure on bronchial reactivity to acetylcholine are also studied. An experimental design based on these tests is described. Also some interesting results by using this design will be dealt with in this report.