Examination of lymph node dissection and surgical treatment for ss gallbladder cancer

Abstract

‹Purpose›
We investigated appropriate lymph node (LN) dissection for ss (and/or pHinf_0-1a) gallbladder cancer (GbCa).
‹Method›
We retrospectively examined result of 371 cases of resected GbCa at our institution. We included 74 cases in which the depth was ss (and/or pHinf_0-1a), D₁ or more LN dissection was performed.
‹Result›
There was a difference in survival rate between curative (5 year survival rate (5ys) 71%) and no curative resection (5ys 38%, P=.0006). The rate of LN metastasis was 55% (41/74). PD was effective in pN (+) Binf (-) cases (5ys: without bile duct resection (BDR) 53%, with BDR 38%, with PD 76%, with or without BDR vs with PD: P=0.045 and 0.055, respectively). PD was not effective in pN (-) Binf (-) cases, and there was no difference in degree of LN dissection between D₁ and D₃. With or without BDR in pBinf (-) cases were also not significant.
‹Conclusion›
Obtaining curative resection is most important. We consider performing (PP) PD in pBinf (-) pN (+) cases. We could not find significance of BDR for LN dissection of ss GbCa.