Abstract
EUS plays a central role in the decision-making process of the treatment of duodenal papillary cancer. One of the important roles is to diagnose the depth of tumor invasion both into the duodenal wall and the pancreas. In addition, whether malignant or benign of enlarged lymph nodes still remains a very important issue to determine the tumor clinical stage. EUS in combination with cutting-edge ultrasonographic procedure such as contrast-enhanced EUS may be promising in the near future.