Abstract
A 85-year-old female underwent endoscopic sphincterotomy 6 years ago for removal of common bile duct stones. Gallstones had been followed up without cholecystectomy. She complained of fever and anorexia for one month, and laboratory data revealed abnormal liver function test. US, CT, MRI and EUS revealed no recurrent bile duct stones, but marked dilatation of biliary tree and flat elevated lesions were seen in body and fundus of gallbladder. Although ERCP and peroral cholangioscopy revealed massive amount of mucin in bile duct, mucin-producing tumor was not detected in bile duct. Extended cholecystectomy performed under diagnosis of mucin-producing gallbladder carcinoma. Post-operative pathological findings revealed papillary adenocarcinoma localized in fundus to neck of gallbladder. The tumor invaded proper muscle layer, but lymph node metastasis or tumor extension to bile duct was not seen. We reviewed reported cases of mucin-producing gallbladder carcinoma and discussed about it.
