Abstract
We report our experience with 3 cases of adenosquamous carcinoma of the extrahepatic bile duct with characteristic of the imaging findings, as well as clinical and pathological findings. All 3 patients were men, whose average age was 72.3 years. The chief complaints were jaundice in 2 patients and abdominal pain in 1 patient. Macroscopic examination of the resected specimen revealed an expansive nodular tumor in 2 patients and an infiltrating nodular tumor in 1 patient. The tumor was 75%, 65%, and 85% part squamous cell carcinoma, respectively, being a mixture of tubular adenocarcinoma and squamous cell carcinoma in all cases. On histological examination, the squamous component was predominant at sites of infiltration. One patient had lymph node metastasis, which was caused by poorly differentiated adenocarcinoma. Imaging of the bile duct revealed focal stricture, with unilateral compression in all patients. EUS and IDUS revealed a mass growing outward from the bile duct with increased internal echo in all patients. Bile duct stricture with unilateral compression, expansive outward growth, and increased internal echo seem to be characteristic of adenosquamous carcinoma of the bile duct.
