Abstract
A 75-year-old man was admitted complaining of abdominal pain and fullness. Ultrasonography revealed the gallbladder with debris, stones and isoechoic tumor measuring 30 mm sited near the gallbladder neck. The tumor was mildly enhanced by CT. By MRI, it demonstrated mildly low intensity on T1-weighted image, mildly high intensity on T2-weighted and high intensity on diffusion-weighted images. Based on these findings, the patient underwent cholecystectomy, resection of the extrahepatic bile duct and regional lymph node dissection (D2) with the preoperative diagnosis of cystic duct carcinoma or carcinoma arising from the gallbladder neck. The tumor was squamous cell carcinoma of the cystic duct. Though postoperative external radiation was applied to surgical margin, the patient died 7 months after the surgery. To our knowledge, this is the first report of primary squamous cell carcinoma of the cystic duct in the English or Japanese literature.