Abstract
We examined the clinical demographics and outcomes in 7 patients with recurrent diseases originated from biliary tract malignancies who underwent local treatments. A female patient with a hepatic metastasis of intrahepatic cholangiocarcinoma undergoing limited hepatic resection but multiple liver metastases was observed soon after surgery. Photodynamic therapy was attempted to local recurrence of hilar bile duct carcinoma and biliary obstruction was released for 11 months. A female patient with liver metastasis from lower bile duct carcinoma underwent ablation therapy but resulted in the tumor progression. A male patient with two liver metastases from gallbladder cancer underwent ablation therapy and limited hepatic resection but multiple liver metastases was observed soon after surgery. Three patients underwent limited hepatic resections for liver metastasis from ampullar carcinoma, who had long disease-free survivals. Photodynamic therapy for ampullar carcinoma was failed in one patient who eventually underwent pancreaticoduodenectomy. This patient had a metachronous liver metastasis and liver resection was effective. In cases with a metachronous liver metastasis from ampullar or extrahepatic biliary carcinomas, surgical exploration may provide better survival. Radicality could not be obtained by ablation or photodynamic therapy, which is a palliative option to improve patient quality and short-period survival.