Abstract
A 70-year-old female was admitted to our hospital with the complaint of upper abdominal pain in August 2011. Diffuse swelling of the pancreas, diffuse irregular narrowing of the main pancreatic duct, lower bile duct stenosis and bile duct wall thickness were observed. Although these findings suggested that she was suffering from autoimmune pancreatitis (AIP) with sclerosing cholangitis, neither anti-nuclear antigen nor an increased serum level of IgG-IgG4 was detected. The biopsy specimens obtained by EUS-FNA revealed no malignancy. The patient was diagnosed as AIP with sclerosing cholangitis. Steroid therapy improved the swelling of pancreas and narrowing of the main pancreatic duct. But, the patient was relapsed, and at last she was diagnosed as B-cell type lymphoblastic leukemia according to several immunohistochemical stainings. After 2 years of chemotherapy, Diffuse swelling of the pancreas was improved, showing complete remission. This patient has no recurrence for over 2 years.
