Abstract
Preoperative biliary drainage by endoscopic biliary stenting (EBS) for distal bile duct stricture due to malignant tumor is controversial. The effect and complication, possibility of post-EBS cholangitis, and factors associated with post-EBS cholangitis were retrospectively analyzed in 115 patients with subsequent pancreaticoduodenectomy after EBS. The mean T-bili before drainage was 6.8mg/dL, but after EBS, the mean T-Bili level decreased to 2.16mg/dL. Complication related to EBS, all of which were pancreatitis, occurred in 6 patients (5.2%). 24 cases (20.9%) developed post-EBS cholangitis. Any factors associated with post-EBS cholangitis were not significant in multi-variant analysis. Preoperative EBS should be performed especially in the cases of which preoperative period is lengthy and in the cases of neo-adjuvant chemotherapy which need jaundice decreased. A new designed PS that can reduce retrograde back flow is awaited.