A case of intrahepatic cholangiocarcinoma in a printing industry worker

Abstract

A 47-year-old man who had worked in the printing industry for twelve years presented to the hospital with severe epigastralgia. After clinical evaluations, a tumor was found in his liver. He was then referred to our institution, where he was diagnosed with intrahepatic cholangiocarcinoma and was underwent chemotherapy. Nevertheless, fever and nausea were apperared, he was performed hepatic trisegmentectomy. Despite the treatment, the patient's intrahepatic cholangiocarcinoma progressed, and he died from tumor-related complications. The resected specimen showed two intrahepatic cholangiocarcinomas in S6 and S8/4, and biliary intraepithelial neoplasia extending to the intrahepatic bile ducts between these two tumors. Herein, we summarize the findings of this case experienced 20 years ago and a review of the literature.