Abstract
A female in her seventies was admitted because of weight loss and high fever. CT of the abdomen showed a low density tumor in the S4, S5 and S8. 18F-fluorodeoxyglucose-positron emission tomography and computed tomography (FDG-PET/CT) showed a high accumulation of 18F-FDG in the tumor of the liver and diffusely increased accumulation in the bone marrow. Because of high WBC count and serum granulocyte colony-stimulating factor (G-CSF) level, preoperative diagnosis was G-CSF producing cholangiocarcinoma. Following right anterior and left medial sectionectomy, the serum G-CSF level as well as the WBC count dropped down to normal range. Histologically, the tumor was composed of squamous cell carcinoma which was stained with anti-G-CSF antibody. Postoperative FDG-PET/CT showed no accumulation in the bone marrow.
