Chemotherapy for biliary cancer

Abstract

It is not uncommon for biliary cancer to have reached at an advanced stage at the time of diagnosis. Even in resectable cases, biliary cancer often recurs soon after surgery. Recently completed randomized studies have shown that the abilities of chemotherapies to prolong the survival period of patients with biliary cancer. These results have led to the rapid growth of interest in the development of new drugs for biliary cancer. Proactive clinical studies examining promising molecular drugs targeting specific mutations and immunocheckpoint inhibitors, which have been successful in patients with non-biliary solid cancers, are now underway for the treatment of this cancer.