2017 Volume 31 Issue 4 Pages 723-730
A 58-year-old woman with a body weight loss was referred to our hospital and had cholelithiasis and gallbladder wall thickness pointed out by CT. She became the follow-up. After 1year 1month. CT and ultrasonography showed a gallbladder tumor with irregular wall thickness and duodenum compression. Gallbladder cancer with duodenum invasion was diagnosed by a close inspection and we performed subtotal stomach preserving pancreaticoduodenectomy with liver resection of lower part of S4 and S5. Histopathological examination revealed the coexistence of adenosquamous cell carcinoma (T3aN1M1 Stage IVB) and spindle cell tumor with transformations between squamous cell carcinoma and adenocarcinoma. Adenosquamous cell carcinoma of the gallbladder was rare gallbladder neoplasms and poor prognosis. This case had dissemination and positive cytodiagnosis, which had never seen by the naked eye. We report a case of adenosquamous cell carcinoma of the gallbladder with so-called carcinosarcoma.