2018 Volume 32 Issue 1 Pages 114-123
The indication for radiotherapy is unresectable non-metastatic locally advanced biliary tract cancer. Recently, stereotactic radiotherapy and intensity modulated radiotherapy is improving survival periods for this disease compared to conventional external beam radiotherapy with combination of intraluminal radiotherapy. Additionally, particle radiotherapy using proton or carbon-ion beam with precipitous dose distribution is expected to be favorable treatment option. The median survival time and 5-year overall survival rate of our study for 41 patients with unresectable non-metastatic hilar cholangiocarcinoma was 23 months and 29%, respectively. These treatment modalities may become increasingly common options as adjuvant for resection, and radical or palliative treatment to biliary duct cancer with some issues such as concurrent chemotherapy, biliary stent, radiation damages, and methods for response evaluation.