2018 Volume 32 Issue 1 Pages 147-152
The patient was a 50-year-old female. Enhanced CT examination revealed an irregularity of the gallbladder wall. Abdominal US screening showed a thickening of the inner hypoechoic layer of about 3mm and low protuberances in some areas of the gallbladder. EUS confirmed the absence of any irregularity or disappearance of the outer strong echo band of the gallbladder, and findings of anomalies whereby the pancreatic duct joined the bile duct outside the proper muscular layer of the duodenum.
Based on the images, we diagnosed gallbladder hyperplasia complicated by pancreatobiliary maljunction. We performed laparoscopic cholecystectomy. Macroscopic images of the gallbladder showed granular mucosa and a lesion with papillary protrusion. The histopathological image showed hyperplasia dominating, and partial biliary intraepithelial neoplasia (BillN)-1. We were able to provide treatment in the early stage of gallbladder hyperplasia including BillN-1. This case proved important in the context of the carcinogenic process in the gallbladder complicated by pancreatobiliary maljunction.
