Risk factors of cholecystitis after stent placement in patient with distal malignant biliary obstruction

Abstract

There are few available data on cholecystitis after Self-Expandable Metallic Stent (SEMS) placement in the patients with malignant distal biliary obstruction. This study evaluated the risk factors for cholecystitis. We analyzed 280 patients; 336 examinations who received endoscopic SEMS placement. Cholecystitis was found in 25 patients. Logistic regression analysis reevaled three independent risk factors for cholecystitis: covered type (p=0.014), tumor invasion to cystic duct (p=0.017), gallbladder stone (P-0.022). Three patients with severe cholecystitis were occurred after insertion of covered-SEMS in pancreatic cancer without tumor involvement of cystic duct. This study suggests that covered-SEMS was a risk factor of cholecystitis after SEMS placement, and that it is concern about the possibility of severe cholecystitis even if tumor does not involve cystic duct.