2019 Volume 33 Issue 2 Pages 255-263
A 60-year-old male was hospitalized due to jaundice. Contrast-enhanced abdominal CT showed stenosis of the lower bile duct and dilatation of the intra- and extrahepatic bile ducts, and the wall of the lower bile duct showed thickening and marked enhancement in the late phase. ERCP showed severe stenosis of the lower bile duct. Biopsy of the lower bile duct led to the diagnosis of squamous carcinoma. The diagnosis of adenosquamous carcinoma of the bile duct was made, and pancreatoduodenectomy was performed. Histopathological examination revealed that the vater papilla side of the lesion mainly consisted of squamous carcinoma, the center of the lesion exhibited a mixed squamous and adenocarcinoma, and the liver side of the lesion predominantly consisted of adenocarcinoma. Comparison of cholangiography and histopathology findings revealed severe stenosis in the area of the squamous carcinoma. Preoperative diagnosis was possible by biopsy of the lesion mainly consisted of squamous carcinoma.