Clinical practice guidelines for the management of biliary tract cancers: major revised points for the third edition

Abstract

An updated edition of clinical practice guidelines for the management of biliary tract cancers was be released on June 2019, after 5 years since the previous version. This new guideline involves 45 clinically important questions including 3 new ones, commentaries against which have been updated/generated on the basis of the articles published between 2012 and 2017. However, related clinical researches during this period were exclusively categorized as retrospective observational study, rather than prospective randomized control trial. Therefore, evidence grade for each commentary was classified as low in most questions (A in 1, B in 2, and C in 42), resulting in minor revision on the whole. In this edition, the guideline functions as textbook for learner in addition to practical guide for clinician. Some emerging problems throughout the bureau work are shared here for the upcoming revision.