2020 Volume 34 Issue 4 Pages 764-771
A 69-year-old woman was diagnosed as unresectable locally advanced gallbladder cancer (LAGBC) with invasion to the right hepatic artery and portal vein. She received chemotherapy with gemcitabine and cisplatin. After 9 courses, the size of the tumor decreased and the metastasis was not identified. We planned conversion surgery. On laparotomy, the right hepatic artery was detached from the tumor. Therefore, we performed extended cholecystectomy, extrahepatic bile duct resection and regional lymphadenectomy. Pathological investigation confirmed poorly differentiated tubular adenocarcinoma, pT2 (SS) N0M0, Stage II, and R0 resection margins. The patient received no adjuvant therapy. 17 months after the surgery, she is alive without recurrence. The consensus of conversion surgery for unresectable LAGBC has not been determined. Further studies are required to establish treatment strategy of conversion surgery for unresectable LAGBC.
