Pathology of intraductal papillary neoplasm of bile duct with reference to four subtypes

Abstract

A total of 165 lesions of intraductal papillary neoplasm of bile duct (IPNB) were pathologically examined with an emphasis on four subtypes (intestinal, gastric, pancreatobiliary and oncocytic subtypes). The intestinal subtype was common followed by gastric, pancreatobiliary and oncocytic subtypes. These four subtypes presented unique histopathological features and pathological, biological features. They were dicussed with a reference to type 1 and 2 subclassification proposed by Japan-Korea experts biliary pathologists. IPNBs were recommended to be evaluated with a reference to four subtypes and type 1 and 2 subclassification.