A case of functional gallbladder disorder with concomitant exacerbations of PBC diagnosed by cholescintigraphy

Abstract

A 48-year-old woman with a chief complaint of postprandial epigastralgia was referred to our hospital. She had been diagnosed with primary biliary cholangitis (PBC) at age 37. We suspected organic common bile duct obstruction by gallstones because of being elevated hepatobiliary enzymes. No abnormalities were found in the computed tomography (CT), magnetic resonance cholangiopancreatography, abdominal ultrasonography, esophagogastroduodenoscopy, and endoscopic ultrasonography. Gallstones and sludge were absent in the gallbladder and biliary tract. The cholescintigraphy showed decreased gallbladder ejection and delayed excretion of drugs from the liver. We concluded functional gallbladder disorder with intrahepatic cholestasis due to PBC. To the best of our knowledge, this is the first report of functional gallbladder disorder with concomitant exacerbations of PBC diagnosed by cholescintigraphy.