2023 Volume 37 Issue 5 Pages 864-872
Despite recent advances in imaging technology with a steadily improved evaluation of localization and the extension of biliary tract cancer, pathological assessment based on tissue sampling is essential for a definitive diagnosis and accurate evaluation of the progression. Furthermore, in the coming era of genomic medicine, high-quality tissue samples from individual patients suitable for comprehensive genomic profiling tests is required to provide personalized medicine based on patients' own genetic information. However, there are various challenges in tissue collection from bile ducts using existing methods. Here, we refer to points to be considered in the preoperative diagnosis of biliary tract cancer, and review the current status of tissue sampling for pathological evaluation by bile duct stricture biopsy and mapping biopsy using existing methods. In addition, we will discuss the features, results to date, and future prospects of the new device, which was developed to overcome various challenges in the diagnosis of biliary tract cancer.
