2024 Volume 38 Issue 5 Pages 719-726
The patient was a 78-year-old man. He was admitted with a weight loss and was incidentally pointed out that the gallbladder was found to have diffuse wall thickening and hepatic infiltration, which led to the diagnosis of gallbladder cancer. He underwent 7 courses of GCS therapy for unresectable gallbladder cancer with enlarged para-aortic lymph nodes and was judged to have a partial response on a CT scan. The patient underwent cholecystectomy with resection of the liver bed, and the postoperative course was uneventful. The pathological examination revealed IgG4-related cholecystitis. Postoperative IgG and IgG4 levels were normal, and there were no symptoms or findings of IgG4-related disease one year after surgery. Isolated IgG4-related cholecystitis is extremely rare and difficult to distinguish from cancer on imaging. Isolated IgG4-related cholecystitis is exceedingly rare and challenging to differentiate from cancer on imaging. This case is considered valuable, and we report it here along with a literature discussion.
