2025 Volume 39 Issue 1 Pages 10-18
Upon returning to the Sixth Research Laboratory of the Second Department of Internal Medicine at Nagoya University (commonly known as "Meidai Ninai Rokken"), my first memorable presentation was on "A Study of Gallbladder Polyps." Subsequently, I was fortunate to be involved in pioneering research, including the world's first observation and study of the bile and pancreatic ducts using an intraductal ultrasound (IDUS) probe and the development of the world's first electronic radial endoscopic ultrasound (EUS). The digitization of EUS enabled contrast imaging even with EUS images.
In the field of metabolic research, my studies extended to pancreatic exocrine insufficiency (PEI) and small intestinal mucosal atrophy, endoscopic verification of the incretin effect in humans, and the relationship between metabolic instability due to PEI and dysbiosis of the gut microbiota. Recently, I have come to recognize the significance of analyzing, regulating, and intervening in the gut microbiota.
In this article, I would like to primarily focus on aspects related to the gut microbiota.
