2025 Volume 39 Issue 2 Pages 164-172
In Japan, the standard treatment for resectable perihilar bile duct cancer is radical surgery and adjuvant chemotherapy with S1. To determine if a tumor is resectable, we must evaluate both host and tumor factors. In particular, it is essential to assess tumor progression and confirm safety. Resection of perihilar cholangiocarcinoma involves different dissection lines of the artery, portal vein, and bile duct. Surgical planning and execution are crucial. Postoperative mortality also tends to be high. Drainage and close observation of blood flow can help avoid serious complications. This includes arterial, portal, and venous flow. Treatment options for unresectable biliary tract cancer have increased in recent years. They are also looking at conversion resection for patients who respond well to these treatments over time. We must generalize the know-how from high-volume centers. This is to make the standard treatment of perihilar cholangiocarcinoma safe and effective.
