2025 Volume 39 Issue 2 Pages 249-258
A female who was referred to our hospital due to jaundice. CT and MRCP revealed extensive tumors from the intrahepatic bile ducts to the distal bile duct. In POCS examination, the tumor in the hilar region appeared as an intraductal tumor thrombus, and based on the EOB-MRI findings, it was determined to be a tumor localized within the bile duct. The patient underwent right hepatectomy. Pathological examination showed that the tumor proliferated in a cast-like manner. The tumor cells proliferated in a cribriform pattern, were negative for MUC1, MUC5AC, and S100P, but showed positive CRP staining, leading to a diagnosis of Type 2 IPNB. This tumor presented a rare pattern of intraductal growth. It is believed that further accumulation of similar cases will clarify its characteristics.
