Abstract
Intraluminal implantation of gallbladder cancer into bile duct is rare. We report a case of gallbladder cancer with intraductal spread curatively treated by hepatopancreaticoduodenectomy. A 59-year-old woman was admitted for upper abdominal pain. Abdominal computed tomography showed tumors in gallbladder and bile duct. Endoscopic retrograde cholangiopancreatography and intraductal ultrasonography revealed pancreaticobiliary maljunction and some papillary tumors in the common bile duct. Histopathological diagnosis from biopsy of the tumor was adenocarcinoma.
Hepatopancreaticoduodenectomy was performed for the neoplasms of gallbladder and bile duct. Papillary tumor of the gallbladder showed massive necrosis, viable tumor showed minimal invasion to the muscularis propria.
Tumors of the cystic duct and common bile duct projected into the lumen in papillary polypoid fashion. The neoplastic cells were limited in the mucosal layer without dysplastic lesion. These cells were similar to the cells of gallbladder tumor.