Abstract
Squamous cell carcinoma of the common bile duct have been reported infrequently since Cabot's first report in 1930. A 68-year-old male with jaundice who proved to have a tumor of the common bile duct. He underwent pancreatoduodenectomy combined with a resection of the haptoduodenal ligament including the bile duct, portal vein and hepatic artery. Histologically, the tumor was a well-differentiated squamous cell carcinoma of the intrapancreatic bile duct with no part of adenocarcinoma, infiltrated to the pancreas very sligytly. No lymph node metastasis was found. Postperatively he passed 25 months with no evidence of recurrence. Concerning the etiology of this tumor, it is theorized that the normal columnar epithelium of the bile duct under the chronic inflammatory stimulus can change into squamous metaplasia and eventually carcinoma. On the other hand, it is also considered that squamous cell carcinomas in these unusual sites are more likely to be due to squamous metaplasia of the adenocarcinoma itself than to malignant transformation of a previously benign metaplastic epithelium.
