Abstract
Out of the 77 cases of surgically resected gallbladder cancer during past 17 years,37 cases (48.1%) were found to have cancer invading into the subserosal layer (ss cancer). The 5-year survival rate of curatively resected ss cancer patients was 31.7%. We investigate, further more, the relation between extent of cancer and prognosis depending on invading facto rs. The 5year survival rate of patients without microscopical hepatic infiltration of cancer cells (hin fnegative patients) among those who were resected curatively was 38.5% whereas one year and eight months was the longest survival for patients with hepatic infiltration of cancer cells (hinf-positive patients). The 5-year survival rate for patients without invasion into the hepa toduodenal ligament (binf-negative patients) was 36.4%, whereas that for binf-positive p atients was 16.6%. The 5-year survival rate for patients without lymphnodes metastasis (n-n egative patients) was 40.1%, while that for n-positive patients was 14.2%. With regard to venous and lymphatic vessel invasion, there were no differences between positive patients and ne gative paients. These results suggest that the operation for gallbladder cancer patients should include not only lymphnodal dissection but also combined resection of the liver, bile duct, duo denum and pancreatic head according to extent of hinf and binf factors.
