2001 Volume 17 Issue 3 Pages 159-164
We performed thermochemotherapy into the pleural cavity for treatment of post-operative malignant pleural effusion in patient with p-stage III B adenocarcinoma. An operation was performed as right upper lobectomy (ND2a) and any lymphnode metastases of cancer were not detected by the pathological examination, but inter- and post-operative effusion cytology were positive. With regard to the application of hyperthermia, malignant pleural effusion after an operation presents a clinical challenge when hyperthermia and chemotherapy are used in combination as a local aggressive treatment. Hyperthermia was performed to the ipsilateral pleural cavity for 35 minutes under the perfusion of CDDP (50mg/body). Post-operative pleural effusion clearly decreased and results of cytology test were negative at twice, during seven months after thermochemotherapy.
