STUDIES ON EFFECTS OF PAROMOMYCIN SULPHATE, BITHIONOL, MEBENDAZOLE AND FLUBENDAZOLE IN THE TREATMENT OF MICE INFECTED WITH PLEROCERCOIDS OF DIPHYLLOBOTHRIUM ERINACEI

Abstract

Mice infected with Diphyllobothrium erinacei plerocercoids were administered orally with paromomycin sulphate, bithionol, mebendazole and flubendazole at the total doses of 10, 000 mg/kg for 200 days or subcutaneously with the drugs at the total doses of 2, 500 mg/kg for 25 days. In spite of the high doses, no difference was observed between the number and weight of larvae recovered from mice in experimental groups and those in control groups.