Abstract
X-ray reflectivity profiles of human lactoferrin adsorbed at water interfaces have been calculated using the structure determined by neutron reflection measurements [Lu et al., Langmuir, 21, 3354 (2005)]. A significant difference in the expected profiles was observed between the folding and the unfolding lactoferrin at the interfaces. Time-resolved X-ray reflectivity measurements for probing the protein unfolding dynamics are proposed.
