Abstract
Poly(trimethylene carbonate) (PTMC) and polylactide (PLA) are of great interest for use in various biomedical materials. To characterizethe surface properties, we measuredtheirstatic water contact angle and the feasibility for immobilization of proteins on various surfaces. The measured contact angles indicated that a PTMC surface can be enrich in hydrophobic segments by changing the external conditions. By contrast, PLA surfacesmaintained constant surface conditions under changing external conditions. Furthermore blended PTMC-PLA showed different surface properties that were based on the properties of PTMC and PLA, and surface enrichment of hydrophobic segments was maintained. The application of this blended surface as a biointerface was studied in terms of the feasibility for protein immobilization. By maintaining enrichment in cholesterol derivatives, blending PTMC with PLA promoted protein immobilization. Hence, we conclude that surface enrichment of cholesterol derivatives can be controlled by blending PLA with PTMC.
