Journal of the Japan Diabetes Society
Online ISSN : 1881-588X
Print ISSN : 0021-437X
ISSN-L : 0021-437X
Case Report
A Case of Type 2 Diabetes Mellitus with Garcin's Syndrome due to Skull Base Purulent Osteomyelitis
Ichiyo KonoKohji Nakano
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2006 Volume 49 Issue 5 Pages 349-353

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Abstract
A 58-year-old woman with type 2 diabetes mellitus had interrupted medical treatment for five years. She suffered from right otitis externa and media by pseudomonas aerginosa after injury to the external acoustic meatus, and recovered by antibiotics for a month with sequela of deafness. Multiple cranial neuropathy (right II, III, IV, V1, VI, VII, IX, and X cranial nerve) progressed acutely four month later, and she was diagnosed with Garcin's syndrome. Pseudomonas aerginosa was detected by cultivation of otorrhea. It became clear by contrast-enhanced MRI with fat suppression that inflammation extended from the right middle ear to the skull base. Contrast-enhanced MRI with fat suppression is useful for detecting osteomyelitis of the skull base. The clinical course in our case indicated that susceptibility of infection in diabetes sometimes led to critical condition.
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© 2006 Japan Diabetes Society
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