Journal of the Japan Diabetes Society
Online ISSN : 1881-588X
Print ISSN : 0021-437X
ISSN-L : 0021-437X
Case Report
Type 2 Diabetes Mellitus Requiring Large-dose Insulin during Severe Acute Pancreatitis
Toru MatsuhashiYasuyuki KiharaMisa ShimadaMasashi TaguchiMitsuo TashiroMitsuyoshi YamamotoMakoto Otsuki
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JOURNAL FREE ACCESS

2008 Volume 51 Issue 1 Pages 19-25

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Abstract

A 63-year-old woman admitted for left hypochondalgia and left back pain on February 27, 2004, had been diagnosed with type 2 diabetes mellitus and treated with oral hypoglycemic agents since 8 years earlier. She was diagnosed with severe acute pancreatitis and treated with a continuous intravenous infusion of rapid insulin. She required 217 units of insulin per day to maintain plasma glucose below 150 mg/dl. The required dose of insulin gradually decreased with improvement of in her condition. Before discharge, her hyperglycemia was successfully controlled with oral hypoglycemic agents without insulin. Hyperglycemia is a risk factor in acute pancreatitis and strict glycemic control plays an important role in improving mortality in severe acute pancreatitis.

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© 2008 Japan Diabetes Society
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