Abstract
A 59-year-old male with type 2 diabetes had been in good glycemic control with intensive insulin therapy. The therapy was switched from insulin to exenatide under continuous glucose monitoring. Hypoglycemia and consecutive hyperglycemia occurred several times soon after the initiation of exenatide and disappeared five days later. Exenatide monotherapy does not generally cause hypoglycemia. However, clinicians should pay attention to the occurrence of abrupt hypoglycemia after the initiation of exenatide, especially in patients with good glycemic control.
