Multiple Insulinomas Associated with Cystic Lesions: A Case Report

Abstract

A 67-year-old man was referred to our hospital due to general malaise, hypoglycemia and a pancreatic tumor. Abdominal computerized tomography, magnetic resonance imaging and endoscopic ultrasonography showed a cystic tumor and hypervascular lesion in the tail of the pancreas. Venous sampling demonstrated that the insulin level in the hepatic vein had dramatically increased due to calcium injection into the splenic artery. The patient underwent distal pancreatectomy, and the presence of multiple cystic insulinomas was subsequently confirmed in the excised specimen of the pancreas. We herein report a rare case of multiple cystic insulinomas.