Journal of the Japan Diabetes Society
Online ISSN : 1881-588X
Print ISSN : 0021-437X
Report of the Committee
A Large-scale, Observational Study to Investigate the Current Status of Diabetic Complications and Their Prevention in Japan: Research Outline and Baseline Data for Type 1 Diabetes - JDCP study 2
[in Japanese]Rimei NishimuraKazuo IzumiYasuaki HayashinoHideki OrikasaMitsuhiko NodaKohjiro UekiNaoko Tajima
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2015 Volume 58 Issue 6 Pages 426-436

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Abstract

The Japan Diabetes Complications and Prevention (JDCP) study is a prospective, large-scale observational study that was designed and conducted to investigate the current state of diabetes management among Japanese patients with type 1 and type 2 diabetes and its relationship with the occurrence of events detected during follow-up, thereby exploring the risk factors for the development and progression of diabetic complications. The study enrolled a total of 6,338 diabetes patients, who ranged from 40-75 years of age and who were treated in an outpatient setting between 2007 and 2009. The primary endpoint of the study was the occurrence of nephropathy, retinopathy, neuropathy, macroangiopathy or periodontal disease. The secondary endpoint was the occurrence of malignancy or mortality. Of the patients who were enrolled, those with type 1 diabetes (n=394) became the focus of this study. Their baseline clinical characteristics were examined. The men/women comprised 44.2 % and 55.8 % of the study population, respectively. Their baseline characteristics were as follows (men/women): mean age (55.3/56.8 years); duration of diabetes (11.9/11.1 years); percentage of patients with a family history of diabetes (22.7 %/35.6 %); BMI (22.4/21.8 kg/m2) (P=0.048); HbA1c (7.9 %/7.7 %); percentage of patients who achieved an HbA1c level of <7 % (23.1 %/26.9 %); systolic blood pressure (SBP) (126.0/124.9 mmHg); and LDL-C (106.1/107.7 mg/dL). The insulin therapy in place among the patients entailed 33.0±17.1 U of insulin as well as 0.58±0.25 U of insulin per 1 kg of body weight; 95.8 % of the patients performed self-monitoring of their blood glucose levels (SMBG).

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© 2015 Japan Diabetes Society
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