The Examination of the Patient Background and Physical Function in Muscle Strength and Quality of Patients With Type 2 Diabetes

Abstract

A decline in the muscle strength (MS) and muscle quality (MQ) has been noted in patients with type 2 diabetes. The aim of this study was to investigate the association between patient characteristics and the maintenance of or reduction in the MS and MQ in patients with type 2 diabetes. A total of 95 type 2 diabetes patients were eligible for this analysis from April 1, 2015, to December 31, 2017 (67 males, 28 females, age: 59.0±14.4 years, duration of diabetes: 6.9±8.6 years, HbA1c: 8.8 %±2.8 %). We compared the patient characteristic, body composition, and physical function between the groups with maintained and decreased MS and MQ values. A logistic regression analysis was used to examine the association between the patient characteristics and a maintained or decreased MS and MQ. Regarding the MS, the body fat percentage was independently related to a decreased MS (odds ratio [OR] 0.93, 95 % confidence interval [CI] 0.88-0.98, p=0.004). Regarding the MQ, the walking speed was independently associated with a maintained MQ (OR 5.86, 95 % CI 1.16-29.64, p=0.033). Our results suggested that the MQ reflects the walking ability more sensitively than the MS in patients with type 2 diabetics.