Abstract
Authors have experienced a typical patient with hyperosmolar nonketotic diabetic coma, traced his clinical course and laboratory findings in details, and discussed the pathogenesis of this disorders.
This patient showed neither ketosis nor acidosis although did markedly hyperglycemic and comatous state. Hyperosmolarity with hypernatremia of this patient was restored rapidly by administering large amount of regular insulin and infusion of saline and 5% of xylitol solution.
The findings that serum ketone bodies, free fatty acids and other lipids were not so elevated suggested some mechanism of suppressed lipid mobilization in this disease.
