Abstract
An autopsied case of thirty-two-year old man with Kimmelstiel-Wilson syndrome associated with pancreatolithiasis and sustained hyperinsulinism was reported with special refrences to the developing mechanism of hypoglycemic attacks, which were recurrently observed in this case.
Clinically, the diagnosis of diabetes mellitus associated with insuloma was strongly suggested, but the only histological evifindingdence in pancreas at autopsy was a marked decrease in the amount of normal structure which was replaced with large amount of fibrous connective tissue. We failed to verify the existence of insuloma in the pancreas in spite of its thorough examination. This, however, does not exclude the possibility of ectopic insuloma.
