Abstract
A radioreceptor assay (RRA), similar to the bioassay that is more essential than radioimmunoassay (RIA), has recently been studied as a measurement of insulin in serum. A sensitive method has been developed for measuring insulin in serum using an insulin receptor solubilized from normnl human placental membranes.
This receptor assay system is specific for insulin and has a sensitivity similar to that of the current radioimmunoassay system.
There was a high degree of correlation between the results of immunoassay and receptor assay over the physiological range of the normal serum insulin level.