Abstract
The relationship between the ability for insulin secretion before treatment and the mode of treatment required for gaining good diabetic control, was studied in moderate or severe diabetic subjects who were nonobese.
The resul is obtained were as follows.
1) There were no differences in ability for insulin secretion among the three groups treated with diet only, oral hypoglycemic agents or insulin.
2) There was no difference in the percentage of subjects treated with diet only, between diabetics with and those without ability for insulin secretion. No patient who had shown insulin secretion was treated with insulin.
3) The percentage of subjects treated with diet only was larger in diabetics whose duration of diabetes was below one year than in those whose duration of diabetes was over one year.
For the purpose of assessing whether a patient could be well controlled with diet only, his duration of diabetes is thought to be a more useful criterion than his ability for insulin secretion before treatment.
