The Effects of Serum Insulin as a Coronary Risk Factor

Abstract

To evaluate the influence of serum insulin as a coronary risk factor, serum immunoreactive insulin, blood glucose and atherogenic index were reviewed in 96 patients with a past myocardial infarction. There was no significant differences in the total sum of blood glucose levels (ΣBG) during a 75 g. oral glucose tolerance test in patients with or without angina pectoris. On the other hand, thetotal sum of immunoreactive insulin (ΣIRI) was larger in the patients with angina pectoris than in those without angina pectoris. Atherogenic index correlated well with ΣIRI in the patients with past myocardial infarction (r=0.63, p<0.001).
These results indicated that hyperinsulinism might be one of the risk factors of coronary sclerosis.