Abstract
In 21 female obese diabetic patients who could not reduce their body weight because of an irregular dinner schedule, combined diet therapy (960 kcal/day) consisting of a diabetic diet for breakfast and lunch and a very low-calorie diet (Optifast (R)) for dinner was prescribed for 2 months in our outpatient clinic. The patients were subsequently switched from combined diet therapy to a diabetic diet (1, 200 kcal/day). Two months of combined diet therapy significantly reduced body weight and %fat.The hyperglycemia and hyperinsulinemia during OGTT observed before therapy were improved after this therapy. HbA1c and plasma lipids were normalized.Even at the end of a year, reduced body weight and normal HbA1c were maintained in 18 patients. Obesity and hyperglycemia had recurred in 3 patients.
These findings indicate that this combined diet therapy is effective in 1) correcting of irregular dinner schedules, 2) maintaining weight loss and 3) improving diabetes mellitus in such patients, suggesting that this therapy would be useful in the treatment of obese diabetics who cannot reduce their body weight because of irregular dinner schedules.
