Journal of the Japan Diabetes Society
Online ISSN : 1881-588X
Print ISSN : 0021-437X
ISSN-L : 0021-437X
A Case of Diabetes Mellitus with Severe Retinopathy Accompanied by Pheochromocytoma: a transient remission of diabetes and complete remission of preproliferative retinopathy after tumorectomy
Yasusi AzamiKeiko TaitouChuji Fujioka
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1993 Volume 36 Issue 12 Pages 937-942

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Abstract
We report a case of diabetes mellitus accompanied by pheochromocytoma. A 68-year-old woman was admitted to our hospital because of uncontrolled diabetes mellitus in April 1991.During this hospitalization, she was newly diagnosed as having pheochromocytoma.Her diabetes had been treated with oral hypoglycemic agents, and then with insulin, during this hospitalization. Immediately after tumorectomy she experienced complete remission of the diabetic state with a dramatic increment in insulin secretion. However, her blood glucose rose again with a slight weight gain four months after tumorectomy. The clinical course suggests that diabtes mellitus was aggravated by pheochromocytoma, in addition to genetic factors, in this patient. The prognosis of diabetes after tumorectomy has not yet been analysed.This patient's clinical course indicates the necessity of following glucose tolerance even after tumorectomy.Although diabetic retinopathy rarely accompanies pheochromocytoma, in this case preproliferative retinopathy was observed before the tumorectomy and diminished postoperatively.
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