Abstract
Risk factors related to the prognosis of diabetic patients were assessed in a follow-up study of 1, 939 NIDDM patients, with mean observation period of 15years, in our institute. The odds ratios of mortality computed in relation to baseline factors were significantly increased in male patients, patiens entering the study alter 45 years, of age fasting glucose level greater than 140mg/dl, hypertension, ischemic ECG changes, diabetic retinopathy, proteinuria, oral hypoglycemic agent treatment and insulin treatment. The baseline factors were compared between patients who were alive versus deceased at the end of follow-up. Older age at onset and at entry, higher values of fasting glucose, systolic and diastolic blood pressures, and an increase in male patients, patients with ischemic ECG changes, diabetic retinopathy, proteinuria, oral hypoglycemic agent treatment and insulin treatment were observed in the deceased patients. Furthermore, multiple logistic analysis indicated significant relations of age at entry, fasting glucose level, hypertension, retinopathy, proteinuria and therapeutic regimen to prognosis. Furthermore, it was found that the baseline factors predictive of the prognosis were different in each age group.
