Journal of the Japan Diabetes Society
Online ISSN : 1881-588X
Print ISSN : 0021-437X
ISSN-L : 0021-437X
The Acute Effect of the Combination Therapy of α-Glucosidase Inhibitor and Exercise on Postprandial Blood Glucose after Lunch in Non-Insulin-Dependent Diabetic Patients
Nobuko ArawakaAkiyo KaritaToshiro YamazakiHiroaki SeinoHiroaki KikuchiHiroaki FujinumaRyuzo Abe
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1999 Volume 42 Issue 2 Pages 143-147

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Abstract
To clarify the acute effects of α-GI and exercise on postprandial blood glucose levels after lunch in NIDDM patients, we examined eight NIDDM patients who took α-GI with diet and exercise therapies. Blood glucose levels after lunch had been higher than 200 mg/dl before commencement of diet therapy in these patients. They were treated with combination therapies according to the following protocols: 1) only diet, 2) diet with α-GI, 3) diet with α-GI and exercise.Each patient performed exercise for 30 min using a bicycle ergometer to test anaerobic threshold levels. In the present study, taking α-GI with diet and exercise therapies showed the greatest decrease in blood glucose levels after lunch in NIDDM patients, as compared with the other therapies. The results suggest that α-GI is more effective in controlling blood glucose in NIDDM patients when supplemented with diet and exercise therapies.
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