Abstract
We studied factors related to death from coronary heart disease (CHD) and cerebro-vascular disease (CVD) in 1, 939 patients with type 2 diabetes mellitus who entered the study during 1960-1974 and were followed up to the end of 1993 (mean observation: 14.9±6.6 years). At the end of follow-up, 1, 000 patients (51.6%) were alive, 880 (45.4%) had died, and 56 (3.0%) could not be followed up. Of the 880 deceased, 111 died of CHD and 128 of CVD. We analyzed the relationship of risk factors to CHD and CVD deaths by mortality, odds ratio, and multiple logistic regression. CHD deaths were found to be related to fasting plasma, blood pressure, ischemic ECG change, serum cholesterol, retinopathy, proteinuria, and treatment type, CVD deaths were found to be related to hypertension, proteinuria, and treatment type. Multiple logistic analysis indicated a significant relatinship to systolic blood pressure, ischemic ECG findings, and serum cholesterol in CHD mortality, and a significant relatinship to hypertension in CVD mortality, in addition to age.
